BI-2852
Product Specifications
CAS Number
2375482-51-0
SKU
C13818-5mg
Target
Ras
Applications
Apoptosis
Smiles
CN1C=C (N=C1) CN2C=CC3=C2C=C (C=C3) CNCC4=C (C5=CC=CC=C5N4) C6C7=C (C=CC (=C7) O) C (=O) N6
Molecular Formula
C31H28N6O2
Additionnal Information
BI-2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells.
Storage Conditions
3 years -20°C powder
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal SR-AI/MSR Antibody [mFluor Violet 500 SE]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
