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JH-RE-06

Product Specifications

CAS Number

1361227-90-8

SKU

C13719-1mg

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

CC (C) CC (=O) C1=C (NC2=C (C=CC (=C2C1=O) [N+] (=O) [O-]) Cl) NC3=C (C=C (C=C3) Cl) Cl

Molecular Formula

C20H16Cl3N3O4

Additionnal Information

JH-RE-06 is a potent REV1-REV7 interface inhibitor with an IC50 of 0.78 μM and Kd value of 0.42 μM, disrupting REV1-POL ζ-mediated mutagenic translesion synthesis (TLS) .

Storage Conditions

3 years -20°C powder

Available Sizes

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