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Brepocitinib (PF-06700841)

Product Specifications

CAS Number

1883299-62-4

Synonyms

PF-841

SKU

C13683-5mg

Target

JAK

Applications

Angiogenesis

Smiles

CN1C=C (C=N1) NC2=NC=CC (=N2) N3CC4CCC (C3) N4C (=O) C5CC5 (F) F

Molecular Formula

C18H21F2N7O

Additionnal Information

Brepocitinib (PF-06700841, PF-841) is a potent inhibitor of Tyk2 and Jak1 with IC50s of 23 nM, 17 nM, 77 nM for Tyk2, Jak1 and Jak2 respectively. It has appropriate in-family selectivity against JAK2 and JAK3.

Storage Conditions

3 years -20°C powder

Available Sizes

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