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A1874

Product Specifications

CAS Number

2064292-12-0

SKU

C13669-1mg

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NCCOCCOCCOCCNC (=O) C4=CC (=C (C=C4) NC (=O) C5C (C (C (N5) CC (C) (C) C) (C#N) C6=C (C=C (C=C6) Cl) F) C7=C (C (=CC=C7) Cl) F) OC) C8=CC=C (C=C8) Cl) C

Molecular Formula

C58H62Cl3F2N9O7S

Additionnal Information

A1874 is a much improved nutlin-based, BRD4-degrading PROTAC and is able to degrade its target protein by 98% with nanomolar potency.

Storage Conditions

3 years -20°C powder

Available Sizes

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