Selpercatinib (LOXO-292)
Product Specifications
CAS Number
2152628-33-4
Synonyms
ARRY-192
SKU
C13665-5mg
Target
C-RET
Applications
Protein Tyrosine Kinase
Smiles
CC (C) (COC1=CN2C (=C (C=N2) C#N) C (=C1) C3=CN=C (C=C3) N4CC5CC (C4) N5CC6=CN=C (C=C6) OC) O
Molecular Formula
C29H31N7O3
Additionnal Information
Selpercatinib (LOXO-292, ARRY-192) is a potent and specific RET (c-RET) inhibitor with IC50 values of 1 nM, 2 nM, 2 nM, 4 nM, 2 nM, 2 nM for WT RET, RET V804M, RET V804L, RET A883F, RET M918T and RET S891A respectively.
Storage Conditions
3 years -20°C powder
Available Sizes
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