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GLPG1837

Product Specifications

CAS Number

1654725-02-6

Synonyms

ABBV-974

SKU

C13600-2mg

Target

CFTR

Applications

Transmembrane Transporters

Smiles

CC1 (CC2=C (C (O1) (C) C) SC (=C2C (=O) N) NC (=O) C3=CC=NN3) C

Molecular Formula

C16H20N4O3S

Additionnal Information

GLPG1837 (ABBV-974) is a novel CFTR potentiator with an EC50 value of 3 nM for F508del, showing enhanced efficacy on CFTR mutants harboring class III mutations compared to Ivacaftor.

Storage Conditions

2 years -80 in solvent

Available Sizes

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