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Serabelisib (TAK-117)

Product Specifications

CAS Number

1268454-23-4

Synonyms

INK-1117, MLN-1117

SKU

C13514-5mg

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

C1COCCN1C (=O) C2=CN=C3N2C=C (C=C3) C4=CC5=C (C=C4) OC (=N5) N

Molecular Formula

C19H17N5O3

Additionnal Information

Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.

Storage Conditions

2 years -80 in solvent

Available Sizes

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