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Alrizomadlin

Product Specifications

CAS Number

1818393-16-6

Synonyms

APG-115, AA-115

SKU

C13484-5mg

Target

MDM2/MDMX

Applications

Apoptosis

Molecular Formula

C34H38Cl2FN3O4

Additionnal Information

Alrizomadlin (APG-115, AA-115) is a highly potent and efficacious inhibitor of MDM2 and binds to MDM2 with IC50 of 3.8 nM. It exhibits potent antiproliferative and apoptogenic activities and also significantly reduces tumor burden and prolonged survival in AML xenograft models.

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