Temuterkib (LY3214996)

Product Specifications

CAS Number

1951483-29-6

SKU

C13475-2mg

Target

ERK

Applications

MAPK

Smiles

CC1 (C2=C (C=C (S2) C3=NC (=NC=C3) NC4=CC=NN4C) C (=O) N1CCN5CCOCC5) C

Molecular Formula

C22H27N7O2S

Additionnal Information

Temuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines.

Storage Conditions

2 years -80 in solvent

Available Sizes

Curated Selection

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