NMS-P118

Product Specifications

CAS Number

1262417-51-5

SKU

C13369-5mg

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

C1CC (CCC1N2CCC (CC2) N3CC4=C (C3=O) C (=CC (=C4) F) C (=O) N) (F) F

Molecular Formula

C20H24F3N3O2

Additionnal Information

NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively) .

Storage Conditions

2 years -80 in solvent

Available Sizes

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