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KU-0060648

Product Specifications

CAS Number

881375-00-4

SKU

C13151-2mg

Target

DNA-PK

Applications

PI3K/Akt/mTOR

Smiles

CCN1CCN (CC1) CC (=O) NC2=C3C4=CC=CC=C4SC3=C (C=C2) C5=CC=CC6=C5OC (=CC6=O) N7CCOCC7

Molecular Formula

C33H34N4O4S

Additionnal Information

KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.

Storage Conditions

2 years -80 in solvent

Available Sizes

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