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Cobimetinib (GDC-0973)

Product Specifications

CAS Number

934660-93-2

Synonyms

RG7420, XL518

SKU

C13147-5mg

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

C1CCNC (C1) C2 (CN (C2) C (=O) C3=C (C (=C (C=C3) F) F) NC4=C (C=C (C=C4) I) F) O

Molecular Formula

C21H21F3IN3O2

Additionnal Information

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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