Cobimetinib (GDC-0973)
Product Specifications
CAS Number
934660-93-2
Synonyms
RG7420, XL518
SKU
C13147-5mg
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
C1CCNC (C1) C2 (CN (C2) C (=O) C3=C (C (=C (C=C3) F) F) NC4=C (C=C (C=C4) I) F) O
Molecular Formula
C21H21F3IN3O2
Additionnal Information
Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.
Storage Conditions
2 years -80 in solvent
Available Sizes
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