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CHZ868

Product Specifications

CAS Number

1895895-38-1

SKU

C13036-5mg

Target

JAK

Applications

Angiogenesis

Molecular Formula

C22H19F2N5O2

Additionnal Information

CHZ868 is an inhibitor of type II JAK2 with an IC50 value of 0.17 μM in EPOR JAK2 WT Ba/F3 cells. CHZ868 demonstrates 60- to 70-fold higher inhibition of JAK1-/TYK2-mediated nuclear STAT1 translocation compared to pan-JAK inhibitors.

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