Dorsomorphin
Product Specifications
CAS Number
866405-64-3
Synonyms
BML-275, Compound C
SKU
C12989-5mg
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
C1CCN (CC1) CCOC2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=CC=NC=C5) N=C3
Molecular Formula
C24H25N5O
Additionnal Information
Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin selectively inhibits the BMP type I receptors ALK2, ALK3 and ALK6. Dorsomorphin is used in promoting specific cell differentiation and inducing cancer cell line autophagy. For cell testing, the water-soluble S7306 Dorsomorphin (Compound C) 2HCl is recommended.
Storage Conditions
2 years -80 in solvent
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
132828-ML405 100 µL
RPS6KB2 (Ribosomal Protein S6 Kinase beta 2, S6K-beta-2, S6K2, 70kD Ribosomal Protein S6 Kinase 2, p70-S6K 2, P70S6K2, p70 Ribosomal S6 Kinase beta, p70 S6 Kinase beta, p70 S6K-beta, p70 S6KB, S6K-beta, p70-beta, S6 Kinase-related Kinase, SRK, Serine/Threonine-protein Kinase 14B, STK14B) (MaxLight 405) discontinued
Ask
View Details