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Pexmetinib

Product Specifications

CAS Number

945614-12-0

Synonyms

ARRY-614

SKU

C12956-5mg

Target

P38 MAPK

Applications

MAPK

Smiles

CC1=CC=C (C=C1) N2C (=CC (=N2) C (C) (C) C) NC (=O) NCC3=C (C=CC (=C3) F) OC4=CC5=C (C=C4) N (N=C5) CCO

Molecular Formula

C31H33FN6O3

Additionnal Information

Pexmetinib is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.

Storage Conditions

2 years -80 in solvent

Available Sizes

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