AZD3839

1227163-84-9

C12904-10mg

BACE

Neuronal Signaling

C1=CC (=CC (=C1) C2 (C3=C (C (=CC=C3) F) C (=N2) N) C4=CC (=NC=C4) C (F) F) C5=CN=CN=C5

C24H16F3N5

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

2 years -80 in solvent