VS-4718 (PND-1186)

1061353-68-1

SR-2156

C12848-5mg

FAK

Protein Tyrosine Kinase

CNC (=O) C1=CC=CC=C1NC2=CC (=NC=C2C (F) (F) F) NC3=C (C=C (C=C3) N4CCOCC4) OC

C25H26F3N5O3

VS-4718 (PND-1186) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis. Phase 1.

2 years -80 in solvent