Lestaurtinib
Product Specifications
CAS Number
111358-88-4
Synonyms
CEP-701, KT-5555
SKU
C12836-5mg
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CC12C (CC (O1) N3C4=CC=CC=C4C5=C6C (=C7C8=CC=CC=C8N2C7=C53) CNC6=O) (CO) O
Molecular Formula
C26H21N3O4
Additionnal Information
Lestaurtinib (CEP-701, KT-5555) is a derivative of the indolocarbazole K252 and a staurosporine analog. It is an orally active inhibitor of receptor protein tyrosine kinases (RPTKs), which inhibits FLT3 and Trk, with an IC50 of 3 nM and < 25 nM, respectively. It also inhibits JAK2 with an IC50 of 0.9 nM.
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