Lestaurtinib

Product Specifications

CAS Number

111358-88-4

Synonyms

CEP-701, KT-5555

SKU

C12836-5mg

Target

FLT3

Applications

Protein Tyrosine Kinase

Smiles

CC12C (CC (O1) N3C4=CC=CC=C4C5=C6C (=C7C8=CC=CC=C8N2C7=C53) CNC6=O) (CO) O

Molecular Formula

C26H21N3O4

Additionnal Information

Lestaurtinib (CEP-701, KT-5555) is a derivative of the indolocarbazole K252 and a staurosporine analog. It is an orally active inhibitor of receptor protein tyrosine kinases (RPTKs), which inhibits FLT3 and Trk, with an IC50 of 3 nM and < 25 nM, respectively. It also inhibits JAK2 with an IC50 of 0.9 nM.