TH588
Product Specifications
CAS Number
1609960-31-7
SKU
C12828-5mg
Target
MTH1
Applications
DNA Damage/DNA Repair
Smiles
C1CC1NC2=NC (=NC (=C2) C3=C (C (=CC=C3) Cl) Cl) N
Molecular Formula
C13H12Cl2N4
Additionnal Information
TH588 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 μM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 μM.
Storage Conditions
2 years -80 in solvent
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
G8750-02F-PE 100 µL
Gr-1 (GR1, Myeloid Differentiation Antigen, Lymphocyte Antigen 6 Complex Locus G, Lymphocyte Antigen 6G, Ly6g, Ly-6G, Ly-6G.1) (PE)
Ask
View Details 
