Sorafenib
Product Specifications
CAS Number
284461-73-0
Synonyms
NSC-724772, BAY 43-9006
SKU
C12661-20mg
Target
Raf
Applications
MAPK
Smiles
CNC (=O) C1=NC=CC (=C1) OC2=CC=C (C=C2) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F
Molecular Formula
C21H16ClF3N4O3
Additionnal Information
Sorafenib is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15096659 1 Vial
Lentiviral human AP5B1 shRNA (UAS) - Lentiviral human AP5B1 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details 
MBS6451095-01 0.1 mL
HSPA1A (Heat Shock 70kD Protein 1A, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B) (HRP)
Sign In for Pricing
View Details MBS6451095-02 5x 0.1 mL
HSPA1A (Heat Shock 70kD Protein 1A, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B) (HRP)
Sign In for Pricing
View Details PA1123-Dylight550 100 µg
Anti-Matrix metalloproteinase-16 MMP16 Antibody Picoband®, Dylight550 Conjugate
Sign In for Pricing
View Details