Leupeptin Hemisulfate

Product Specifications

CAS Number

103476-89-7

SKU

C12650-10mg

Target

Cysteine Protease

Applications

Proteases

Smiles

CC (C) CC (C (=O) NC (CC (C) C) C (=O) NC (CCCN=C (N) N) C=O) NC (=O) C.CC (C) CC (C (=O) NC (CC (C) C) C (=O) NC (CCCN=C (N) N) C=O) NC (=O) C.OS (=O) (=O) O

Molecular Formula

C20H38N6O4.1/2H2SO4

Additionnal Information

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases. It inhibits cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 μM), and kallikrein (Ki = 19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin.