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Birabresib (OTX015)

Product Specifications

CAS Number

202590-98-5

Synonyms

MK 8628

SKU

C12633-2mg

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NC4=CC=C (C=C4) O) C5=CC=C (C=C5) Cl) C

Molecular Formula

C25H22ClN5O2S

Additionnal Information

Birabresib (OTX015, MK 8628) is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4 in cell-free assays. Birabresib inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

Storage Conditions

2 years -80 in solvent

Available Sizes

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