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PF-562271 HCl

Product Specifications

CAS Number

939791-41-0

SKU

C12630-5mg

Target

FAK

Applications

Protein Tyrosine Kinase

Smiles

CN (C1=C (C=CC=N1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) C4) S (=O) (=O) C.Cl

Molecular Formula

C21H21ClF3N7O3S

Additionnal Information

PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.

Storage Conditions

2 years -80 in solvent

Available Sizes

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