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Alvelestat (AZD9668)

Product Specifications

CAS Number

848141-11-7

Synonyms

Avelestat

SKU

C12530-5mg

Target

Serine Protease

Applications

Proteases

Smiles

CC1=C (C=C (C (=O) N1C2=CC=CC (=C2) C (F) (F) F) C (=O) NCC3=NC=C (C=C3) S (=O) (=O) C) C4=CC=NN4C

Molecular Formula

C25H22F3N5O4S

Additionnal Information

Alvelestat (AZD9668, Avelestat) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. Phase 2.

Storage Conditions

2 years -80 in solvent

Available Sizes

Frequently Asked Questions

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