Bisindolylmaleimide IX (Ro 31-8220) Mesylate
Product Specifications
CAS Number
138489-18-6
SKU
C12522-10mg
Target
PKC
Applications
Cytoskeletal Signaling
Smiles
CN1C=C (C2=CC=CC=C21) C3=C (C (=O) NC3=O) C4=CN (C5=CC=CC=C54) CCCSC (=N) N.CS (=O) (=O) O
Molecular Formula
C25H23N5O2S.CH4O3S
Additionnal Information
Bisindolylmaleimide IX (Ro 31-8220 Mesylate) is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3β and S6K1.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880225-500 1x 500 µL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471081-500 1x 500 µL
CD45RO (190-2F2.5), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680043-500 1x 500 µL
P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680994-500 1x 500 µL
TNF alpha (J2D10), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042848-100 1x 100 µL
Fibronectin (Fn-3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400902-100 1x 100 µL
Nucleolin (NCL/902), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details