ML347

Product Specifications

CAS Number

1062368-49-3

Synonyms

LDN-193719

SKU

C12481-5mg

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

COC1=CC=C (C=C1) C2=CN3C (=C (C=N3) C4=C5C=CC=NC5=CC=C4) N=C2

Molecular Formula

C22 H16 N4 O

Additionnal Information

ML347 (LDN-193719) is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.

Storage Conditions

2 years -80 in solvent

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