IWR-1-endo

Product Specifications

CAS Number

1127442-82-3

Synonyms

Endo-IWR 1, IWR-1

SKU

C12428-10mg

Target

Wnt/beta-catenin

Applications

Cytoskeletal Signaling

Smiles

C1C2C=CC1C3C2C (=O) N (C3=O) C4=CC=C (C=C4) C (=O) NC5=CC=CC6=C5N=CC=C6

Molecular Formula

C25H19N3O3

Additionnal Information

IWR-1-endo (endo-IWR 1, IWR-1) is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells expressing Wnt3A, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.

Storage Conditions

2 years -80 in solvent

Available Sizes

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