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IWP-2

Product Specifications

CAS Number

686770-61-6

SKU

C12427-10mg

Target

Wnt/beta-catenin

Applications

Cytoskeletal Signaling

Smiles

CC1=CC2=C (C=C1) N=C (S2) NC (=O) CSC3=NC4=C (C (=O) N3C5=CC=CC=C5) SCC4

Molecular Formula

C22H18N4O2S3

Additionnal Information

IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.

Storage Conditions

2 years -80 in solvent

Available Sizes

Curated Selection

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