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LY2090314

Product Specifications

CAS Number

603288-22-8

SKU

C12415-5mg

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1CCN (CC1) C (=O) N2CCN3C=C (C4=CC (=CC (=C43) C2) F) C5=C (C (=O) NC5=O) C6=CN=C7N6C=CC=C7

Molecular Formula

C28H25FN6O3

Additionnal Information

LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases.

Storage Conditions

2 years -80 in solvent

Available Sizes

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