What is the catalog number for Merestinib (LY2801653)?

The catalog number for Merestinib (LY2801653) is C12382.

What sizes are available for Merestinib (LY2801653)?

Merestinib (LY2801653) is available in the following size(s): 5 mg, 10 mM / 1 mL, 25 mg.

How many pack sizes does Merestinib (LY2801653) come in?

Merestinib (LY2801653) is available in 3 different pack sizes.

Is Merestinib (LY2801653) in stock?

Merestinib (LY2801653) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Merestinib (LY2801653)?

Merestinib (LY2801653) is requires dry ice shipping.

Merestinib (LY2801653)

Product Specifications

CAS Number

1206799-15-6

SKU

C12382-5mg

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CC1=CC=C (C (=O) N1C2=CC=C (C=C2) F) C (=O) NC3=CC (=C (C=C3) OC4=C (C=C5C (=C4) C=NN5C) C6=CNN=C6) F

Molecular Formula

C30H22F2N6O3

Additionnal Information

Merestinib (LY2801653) is a type-II ATP competitive, slow-off inhibitor of Met (c-Met) tyrosine kinase with a dissociation constant (Ki) of 2 nM, a pharmacodynamic residence time (Koff) of 0.00132 min (-1) and t1/2 of 525 min. Merestinib (LY2801653) also inhibits MST1R, AXL, ROS1, MKNK1/2, FLT3, MERTK, DDR1 and DDR2 with IC50 of 11 nM, 2 nM, 23 nM, 7 nM, 7 nM, 10 nM, 0.1 nM and 7 nM, respectively.