GDC-0152
Product Specifications
CAS Number
873652-48-3
SKU
C12380-10mg
Target
IAP
Applications
Apoptosis
Smiles
CC (C (=O) NC (C1CCCCC1) C (=O) N2CCCC2C (=O) NC3=C (N=NS3) C4=CC=CC=C4) NC
Molecular Formula
C25H34N6O3S
Additionnal Information
GDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
131016-Biotin 100 µL
PCTK1 (CDK16, Cyclin-dependent Kinase 16, Cell Division Protein Kinase 16, PCTAIRE-motif Protein Kinase 1, Serine/Threonine-protein Kinase PCTAIRE-1, FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE) (Biotin)
Sign In for Pricing
View Details MBS1228298-01 0.02 mg (E-Coli)
Recombinant Marthasterias glacialis G2/mitotic-specific cyclin-B
Sign In for Pricing
View Details MBS1228298-02 0.02 mg (Yeast)
Recombinant Marthasterias glacialis G2/mitotic-specific cyclin-B
Sign In for Pricing
View Details