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MK-28

Product Specifications

CAS Number

864388-65-8

SKU

C12339-5mg

Target

PERK

Applications

Apoptosis

Molecular Formula

C24H20N4O2

Additionnal Information

MK-28 is a potent and selective activator of PERK. MK-28 exhibits an IC50 ~3-fold higher than CCT020312 in rescuing mutant huntingtin protein (mHtt) -expressing striatal neurons from apoptosis. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.

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