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CPI-1612

Product Specifications

CAS Number

2374971-81-8

SKU

C12282-5mg

Target

Epigenetic Reader Domain

Applications

Epigenetics

Molecular Formula

C27H26N6O

Additionnal Information

CPI-1612 is a highly potent, orally active inhibitor of EP300/CBP histone acetyltransferase (HAT) . It displays an IC50 of 8.0 nM for EP300 HAT. CPI-1612 suppresses H3K27 acetylation in vivo and exhibits efficacy in JEKO-1 mantle cell lymphoma xenograft at a low dose. CPI-1612 displays anticancer activity.

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