Ningetinib
Product Specifications
CAS Number
1394820-69-9
Synonyms
CT-053, DE-120, CT053PTSA
SKU
C12276-5mg
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C (=O) N (N1C) C2=CC=CC=C2) C (=O) NC3=CC (=C (C=C3) OC4=C5C=CC (=CC5=NC=C4) OCC (C) (C) O) F
Molecular Formula
C31H29FN4O5
Additionnal Information
Ningetinib (CT-053, DE-120, CT053PTSA) is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity.
Storage Conditions
3 years -20°C powder
Available Sizes
Curated Selection
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