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Ningetinib

Product Specifications

CAS Number

1394820-69-9

Synonyms

CT-053, DE-120, CT053PTSA

SKU

C12276-5mg

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C (=O) N (N1C) C2=CC=CC=C2) C (=O) NC3=CC (=C (C=C3) OC4=C5C=CC (=CC5=NC=C4) OCC (C) (C) O) F

Molecular Formula

C31H29FN4O5

Additionnal Information

Ningetinib (CT-053, DE-120, CT053PTSA) is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity.

Storage Conditions

3 years -20°C powder

Available Sizes

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