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Thalidomide-O-COOH (Cereblon ligand 3)

Product Specifications

CAS Number

1061605-21-7

Synonyms

E3 ligase Ligand 3

SKU

C12215-5mg

Target

E3 Ligase

Applications

Ubiquitin

Smiles

C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) OCC (=O) O

Molecular Formula

C15H12N2O7

Additionnal Information

Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3), a Thalidomide-based Cereblon (CRBN) ligand, is used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs (Proteolysis Targeting Chimera) .

Storage Conditions

3 years -20°C powder

Available Sizes

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