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H-1152 dihydrochloride

Product Specifications

CAS Number

871543-07-6

Synonyms

H-1152 2HCl

SKU

C11709-5mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

Cl.Cl.CC1CNCCCN1[S] (=O) (=O) C2=CC=CC3=C2C (=CN=C3) C

Molecular Formula

C16H23Cl2N3O2S

Additionnal Information

H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK) . H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.

Storage Conditions

3 years -20°C powder

Available Sizes

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