Motesanib (AMG-706)

Product Specifications

CAS Number

453562-69-1

SKU

C11356-10mg

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1 (CNC2=C1C=CC (=C2) NC (=O) C3=C (N=CC=C3) NCC4=CC=NC=C4) C

Molecular Formula

C22H23N5O

Additionnal Information

Motesanib (AMG-706) is an orally bioavailable receptor tyrosine kinase inhibitor with IC50 values of 2 nM, 3 nM, 6 nM, 8 nM, 84 nM, 59 nM for VEGFR1, VEGFR2, VEGFR3, Kit, PDGFR and Ret, respectively.

Storage Conditions

3 years -20°C powder

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