NU2058
Product Specifications
CAS Number
161058-83-9
Synonyms
O (6) -Cyclohexylmethylguanine
SKU
C10906-10mg
Target
CDK
Applications
Cell Cycle
Smiles
C1CCC (CC1) COC2=NC (=NC3=C2NC=N3) N
Molecular Formula
C12H17N5O
Additionnal Information
NU2058 (O (6) -Cyclohexylmethylguanine) is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.
Storage Conditions
2 years -80 in solvent
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