What is the catalog number for Simeprevir?

The catalog number for Simeprevir is C10634.

What sizes are available for Simeprevir?

Simeprevir is available in the following size(s): 5 mg, 25 mg, 100 mg.

How many pack sizes does Simeprevir come in?

Simeprevir is available in 3 different pack sizes.

Is Simeprevir in stock?

Simeprevir is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Simeprevir?

Simeprevir is requires dry ice shipping.

Simeprevir

Product Specifications

CAS Number

923604-59-5

Synonyms

TMC435, TMC-435350

SKU

C10634-5mg

Target

HCV Protease

Applications

Proteases

Smiles

CC1=C (C=CC2=C1N=C (C=C2OC3CC4C (C3) C (=O) N (CCCCC=CC5CC5 (NC4=O) C (=O) NS (=O) (=O) C6CC6) C) C7=NC (=CS7) C (C) C) OC

Molecular Formula

C38H47N5O7S2

Additionnal Information

Simeprevir is a competitive, reversible, macrocyclic, noncovalent hepatitis C virus (HCV) NS3/4A protease inhibitor that acts directly against the hepatitis C virus. It has a medium inhibitory concentration (IC50) <13 nM for all HCV NS3/4A enzymes (genotypes 1a, 1b, 2, 4, 5, and 6), but has an IC50 value of 37 nM for genotype 3.