Daminozide
Product Specifications
CAS Number
1596-84-5
Synonyms
Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH
SKU
C10443-100mg
Target
Histone Demethylase
Applications
Epigenetics
Molecular Formula
C6H12N2O3
Additionnal Information
Daminozide (Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH) is a plant growth regulator that selectively inhibits human KDM2/7 histone demethylases, with IC50 of 0.55 μM for PHF8 (KDM7B), 1.5 μM for KDM2A, and 2.1 μM for KIAA1718 (KDM7A) . It shows over 100-fold selectivity for the KDM2/7 subfamily compared to other histone demethylase subfamilies, with significantly weaker activity against enzymes such as KDM3A with IC50 of 127 μM.
Storage Conditions
2 years -80 in solvent
Available Sizes
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