Tenofovir alafenamide hemifumarate

CC (C) OC (=O) C (C) N[P] (=O) (COC (C) C[N]1C=NC2=C (N) N=CN=C12) OC3=CC=CC=C3.CC (C) OC (=O) C (C) N[P] (=O) (COC (C) C[N]4C=NC5=C (N) N=CN=C45) OC6=CC=CC=C6.OC (=O) \C=C\C (O) =O

Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.