Citrullinated amyloid-β (1-42) peptide (human)

Citrullinated amyloid-β (1-42) peptide (human) (Citrullinated Aβ (1-42) ) is a modified form of β-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified β-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified Aβ42, it forms protofibrils comprised of parallel β-sheets[1].

Product Specifications

Product Name Alternative

Citrullinated Aβ (1-42) ; Citrullinated Aβ42

UNSPSC

12352209

Target

Amyloid-β

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/citrullinated-amyloid-β-1-42-peptide-human.html

Purity

97.88

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NC(C)C(NC(CCC(O)=O)C(NC(CC1=CC=CC=C1)C(NC(CCCNC(N)=O)C(NC(CC2=CNC=N2)C(NC(CC(O)=O)C(NC(CO)C(NCC(NC(CC3=CC=C(C=C3)O)C(NC(CCC(O)=O)C(NC(C(C)C)C(NC(CC4=CNC=N4)C(NC(CC5=CNC=N5)C(NC(CCC(N)=O)C(NC(CCCCN)C(NC(CC(C)C)C(NC(C(C)C)C(NC(CC6=CC=CC=C6)C(NC(CC7=CC=CC=C7)C(NC(C)C(NC(CCC(O)=O)C(NC(CC(O)=O)C(NC(C(C)C)C(NCC(NC(CO)C(NC(CC(N)=O)C(NC(CCCCN)C(NCC(NC(C)C(NC(C(C)CC)C(NC(C(C)CC)C(NCC(NC(CC(C)C)C(NC(CCSC)C(NC(C(C)C)C(NCC(NCC(NC(C(C)C)C(NC(C(C)C)C(NC(C(C)CC)C(NC(C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CC(O)=O)N