2'-Deoxy-2'-fluorocytidine
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].
Product Specifications
CAS Number
10212-20-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluorocytidine.html
Concentration
10mM
Purity
99.98
Solubility
H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@H]1[C@@H](F)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1CO
Molecular Formula
C9H12FN3O4
Molecular Weight
245.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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