2'-Deoxy-2'-fluorocytidine

2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].

Product Specifications

CAS Number

[10212-20-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-deoxy-2-fluorocytidine.html

Concentration

10mM

Purity

99.98

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]1[C@@H](F)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1CO

Molecular Formula

C9H12FN3O4

Molecular Weight

245.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99.