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Harmine

Product Specifications

CAS Number

442-51-3

Synonyms

Telepathine

SKU

C09692-25mg

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

CC1=NC=CC2=C1NC3=C2C=CC (=C3) OC

Molecular Formula

C13H12N2O

Additionnal Information

Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs) . Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.

Storage Conditions

2 years -80 in solvent

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