What is the catalog number for PF-477736?

The catalog number for PF-477736 is C08953.

What sizes are available for PF-477736?

PF-477736 is available in the following size(s): 5 mg, 10 mM / 1 mL, 50 mg.

How many pack sizes does PF-477736 come in?

PF-477736 is available in 3 different pack sizes.

Is PF-477736 in stock?

PF-477736 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for PF-477736?

PF-477736 is requires dry ice shipping.

PF-477736

Product Specifications

CAS Number

952021-60-2

Synonyms

PF-736, PF-00477736

SKU

C08953-5mg

Target

Chk

Applications

Cell Cycle

Smiles

CN1C=C (C=N1) C2=C3C=NNC (=O) C4=C3C (=CC (=C4) NC (=O) C (C5CCCCC5) N) N2

Molecular Formula

C22H25N7O2

Additionnal Information

PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.