PF-477736
Product Specifications
CAS Number
952021-60-2
Synonyms
PF-736, PF-00477736
SKU
C08953-5mg
Target
Chk
Applications
Cell Cycle
Smiles
CN1C=C (C=N1) C2=C3C=NNC (=O) C4=C3C (=CC (=C4) NC (=O) C (C5CCCCC5) N) N2
Molecular Formula
C22H25N7O2
Additionnal Information
PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.
Storage Conditions
2 years -80 in solvent
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7225861-01 48 Well
Sheep ATPase family AAA domain-containing protein 3B (ATAD3B) ELISA Kit
Ask
View Details 
MBS7225861-02 96 Well
Sheep ATPase family AAA domain-containing protein 3B (ATAD3B) ELISA Kit
Ask
View Details MBS7225861-03 5x 96 Well
Sheep ATPase family AAA domain-containing protein 3B (ATAD3B) ELISA Kit
Ask
View Details MBS7225861-04 10x 96 Well
Sheep ATPase family AAA domain-containing protein 3B (ATAD3B) ELISA Kit
Ask
View Details